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Merchant, Emily Klancher; O’Keefe, Meaghan (Ed.)DNA, Race, and Reproduction helps readers inside and outside of academia engage with the current genomic landscape. The volume brings together experts in law, medicine, religion, history, anthropology, philosophy, and genetics to investigate how scientists, medical professionals, and laypeople use genomic concepts to construct racial identity and make reproductive decisions. It interrogates how DNA figures in the reproduction of racialized bodies and the racialization of reproduction and examines the privileged position from which genomic knowledge claims to speak about human bodies, societies, and activities. The book begins from the premise that reproduction forces a confrontation between biomedical, scientific, and popular understandings of genetics, and that those understandings are often racialized. It therefore centers reproduction as both a site of analysis and an analytic lens.more » « lessFree, publicly-accessible full text available January 7, 2026
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Oziolor, Elias M.; Reid, Noah M.; Yair, Sivan; Lee, Kristin M.; Guberman VerPloeg, Sarah; Bruns, Peter C.; Shaw, Joseph R.; Whitehead, Andrew; Matson, Cole W. (, Science)null (Ed.)Radical environmental change that provokes population decline can impose constraints on the sources of genetic variation that may enable evolutionary rescue. Adaptive toxicant resistance has rapidly evolved in Gulf killifish ( Fundulus grandis ) that occupy polluted habitats. We show that resistance scales with pollution level and negatively correlates with inducibility of aryl hydrocarbon receptor (AHR) signaling. Loci with the strongest signatures of recent selection harbor genes regulating AHR signaling. Two of these loci introgressed recently (18 to 34 generations ago) from Atlantic killifish ( F. heteroclitus ). One introgressed locus contains a deletion in AHR that confers a large adaptive advantage [selection coefficient ( s ) = 0.8]. Given the limited migration of killifish, recent adaptive introgression was likely mediated by human-assisted transport. We suggest that interspecies connectivity may be an important source of adaptive variation during extreme environmental change.more » « less
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